000			01869nam a22001817a 4500
003			OSt
005			20250321134605.0
008			250321b |||||||| |||| 00| 0 eng d
040			_cNVSU
100			_aNoja, Jendy V.
245			_aIn vivo hemostatic activity of siam weed (chromolaena odorata) leaf extract in albino rats/ _cJendy V. Noja
260			_aBayombong: _bNueva Vizcaya State University, _c2019.
300			_axii, 35 leaves : _billustrations, photos ; _c28 cm.
500			_aThe experiment was conducted to evaluate the hemostatic activity of Siam weed (Chromolaena odorata) in rats. Parameters involved in the study were effect in length of bleeding and coagulation time. Fifteen rats were used in the study. The study was laid out following the complete randomized design (CRD) with five treatments, each treatment with three replicates with the following treatments: Treatment 1-Positive control Vitamin K (phytomenadione), Treatment 2-negative control (distilled water), Treatment 350% odorata ethanol dried leaf extract, Treatment 4-70% C odorata ethanol dried leaf extract, Treatment 5-95% C. odorata ethanol dried leaf extract. Based on the result of the study, C. odorata ethanolic leaf extract exhibited hemostatic activity comparable with vitamin K. Treatment 5 (95% ethanol dried leaf extract) obtained the shortest bleeding time among other treatments and is comparable to T1 (vitamin K) positive control. For practical means and under emergency situations. C odorata leaf extract could be an alternative source as procoagulant. On the other hand, blood coagulation evaluation for C. odorata ethanolic extract displays no significant results. However, all results are within normal reference interval.
500			_aThesis (Doctor of Veterinary Medicine)
504			_aincludes appendices and bibliographical references.
942			_2ddc _cU _n0
999			_c314 _d314