01481nam a22001577a 4500003000400000005001700004008004100021040000900062100002400071245013100095260005500226300006900281500087400350500004301224504005601267OSt20250331092729.0250331b        |||||||| |||| 00| 0 eng d  cNVSU  aTolentino, Carlo G.  aEffectivity of tawa-tawa (euphorbia hirta) in heparin-induced thrombocytopenia in dogs (canis familiaris)/cCarlo G. Tolentino  aBayombong:bNueva Vizcaya State University,c2015.  axiv, 60 leaves :billustrations (some colored), photos ;c28 cm.  aThe study was conducted to determine the platelet increasing effect of tawa-tawa (Euphorbia hiria) capsules in heparin induced thrombocytopenia in dogs The antithrombocytopenic activity of E. hirta was evaluated using platelet count, clotting time and bleeding time determination. 

Fifteen dogs were used in the study. An experiment was done with three treatments having 5 replicates each and was randomly distributed to the cages using the Complete Randomized Design. 
The study at 48 hours posts treatment of heparin, showed that platelet count of experimental animals under treatment 3 starts to increase while the platelet counts of treatments 1 and 2 starts to increase after 72 hours.

The result of the study indicates that the clotting and bleeding time of dogs induced with thrombocytopenia using heparin at a dose of 200 IU/kg body weight were not affected.
  aThesis (Doctor of Veterinary Medicine)  aIncludes appendices and bibliographical references.