Antibacterial efficacy of combined leaf and root extract of pink periwinkle (catharanthus roseus (l.) g.don) against escherichia coli, staphylococcus aureus and methicillin – resistant staphylococcus aureus in vitro/ (Record no. 361)
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| 000 -LEADER | |
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| fixed length control field | 02534nam a22001817a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250321153050.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250321b |||||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | NVSU |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Umlano, Norin Grace T. |
| 245 ## - TITLE STATEMENT | |
| Title | Antibacterial efficacy of combined leaf and root extract of pink periwinkle (catharanthus roseus (l.) g.don) against escherichia coli, staphylococcus aureus and methicillin – resistant staphylococcus aureus in vitro/ |
| Statement of responsibility, etc. | Norin Grace T. Umlano |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Bayombong: |
| Name of publisher, distributor, etc. | Nueva Vizcaya State University, |
| Date of publication, distribution, etc. | 2018. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | xv, 54 leaves : |
| Other physical details | illustrations, photos ; |
| Dimensions | 28 cm. |
| 500 ## - GENERAL NOTE | |
| General note | The study compared the in-vitro antibacterial efficacy of combined pink periwinkle (Catharanthus roseus) leaf and root ethanol extract with the commercially available antibiotics (gentamicin, penicillin and trimethoprim-sulfamethoxazole) and identified the most effective concentration capable of inhibiting the growth of Escherichia coli, Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA). The study was carried out using standard procedure. The extraction was achieved using mortar and pestle and blender with 95% ethanol as solvent. Water bath was used to get pure extract of the plant. The study was laid out in a completely randomized design (CRD) with the following treatments Treatment 1 (positive control) gentamicin, penicillin and trimethoprim-sulfamethoxazole, Treatment 2-75% combined pink periwinkle leaf and root extract, Treatment 3- 50% combined pink periwinkle leaf and root extract: Treatment 4-23% combined pink periwinkle leaf and root extract; Treatment 5 (negative control) -distilled water and Treatment 6 (negative control) ethanol. Each treatment was replicated three times.<br/>Based on the results of the study, the ethanol extract of combined leaf and root of pink periwinkle is not effective as antibacterial against Staphylococcus aureus in comparison to penicillin. The combined pink periwinkle leaf and root ethanol extract exhibited a moderate activity at 75% concentration at 12 hours of incubation but has a lower efficacy compared to gentamicin as an antibacterial against Escherichia coli. The ethanol extract of combined leaf and root of pink periwinkle showed moderate activity against methicillin-resistant Staphylococcus aureus (MRSA) and can be used as an alternative to trimethoprim-sulfamethoxazole.<br/> |
| 500 ## - GENERAL NOTE | |
| General note | Thesis (Doctor of Veterinary Medicine) |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | includes appendices and bibliographical references. |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Undergraduate Research |
| Suppress in OPAC | No |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Source of acquisition | Total checkouts | Full call number | Barcode | Date last seen | Price effective from | Koha item type |
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| Dewey Decimal Classification | Nueva Vizcaya State University - Bayombong Campus | Nueva Vizcaya State University - Bayombong Campus | General Reference Section | 03/21/2025 | Donation | U (DVM) Um52a 2018 | U1226 | 03/21/2025 | 03/21/2025 | Undergraduate Research |
